(DOWNLOAD) "Fast Facts: Comprehensive Genomic Profiling" by B.L. Rapoport, G. Troncone, F. Schmitt & S. Nayler * eBook PDF Kindle ePub Free
eBook details
- Title: Fast Facts: Comprehensive Genomic Profiling
- Author : B.L. Rapoport, G. Troncone, F. Schmitt & S. Nayler
- Release Date : January 03, 2020
- Genre: Genetics,Books,Professional & Technical,Medical,
- Pages : * pages
- Size : 8413 KB
Description
Cancer is a multifaceted disease in which genetic changes induce uncontrolled tumor growth. Genomic characterization of cancer is now leading to better diagnostic, prognostic and predictive biomarkers, and effective individualized management. 'Fast Facts: Comprehensive Genomic Profiling' provides a crash course in the science, methods and application of genomic profiling. Assuming only the most basic knowledge – or memory – of cell biology, the authors provide an overview of DNA and RNA biology and next-generation sequencing. This sets in context the descriptions of prognostic and predictive biomarkers for different cancer types and genomic-based treatments. Finally, but importantly, some of the practicalities of gaining and interpreting genomic information are described. Whether you need a primer or a refresher, this short colorful book demystifies this complex subject. Contents: • Genetic mutations and biomarkers • Understanding next-generation sequencing • Elements of comprehensive genomic profiles • Role in precision oncology • Predictive and prognostic biomarkers • Overcoming barriers to genotype-directed therapy